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Handbook of Experimental Pharmacology

Anion Channels and Transporters

Handbook of Experimental Pharmacology -Band 283

This book provides an overview on recent progress in anion channels and transporters. It covers multiple scales of analysis ranging from studying the molecular basis of function at atomic resolution to ce…

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Drug Delivery and Targeting

Handbook of Experimental Pharmacology -Band 284

Since the publication of the Handbook of Experimental Pharmacology Vol. 197 in 2010 there have been important advances in drug development, drug delivery and more recently drug targeting. This is in p…

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Endolysosomal Voltage-Dependent Cation Channels

Handbook of Experimental Pharmacology -Band 278

This book covers the molecular structures and the cellular and in vivo function of endosomes and lysosomes, i.e. intracellular vesicles which are involved in many cellular processes such as endocytosis, i…

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From Obesity to Diabetes

Handbook of Experimental Pharmacology -Band 274

Obesity is a major risk factor for the development of type 2 diabetes and its associated complications, a major socio-economic burden for health care systems. The worldwide prevalence of obesity doubled s…

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Human iPSC-derived Disease Models for Drug Discovery

Handbook of Experimental Pharmacology -Band 281

Since their development a decade ago, human induced pluripotent stem cells (iPSC) have revolutionized the study of human disease, given rise to regenerative medicine technologies, and provided exceptional…

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Metabolomics and Its Impact on Health and Diseases

Handbook of Experimental Pharmacology -Band 277

This volume of the Handbook of Experimental Pharmacology, which celebrated its 100th anniversary in 2019, addresses the rapidly growing and evolving field of metabolomics. It has been compiled and designe…

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Pharmacology of Immunosuppression

Handbook of Experimental Pharmacology -Band 272

The goal of this book is to provide a guide and detailed review of immunosuppression in terms of molecular mechanisms of action, side effects and clinical trials that validated their utility. This include…

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Precision Medicine

Handbook of Experimental Pharmacology -Band 280

The rapidly increased understanding of the molecular background of complex diseases facilitated the development of highly advanced therapeutic concepts. Such concepts aiming to consider individual signatu…

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Sex and Gender Effects in Pharmacology

Handbook of Experimental Pharmacology -Band 282

Biological sex and gender have a tremendous impact on the efficacy and safety of pharmacological interventions in virtually every disease state. This book presents a comprehensive and up-to-date overview …

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