Rong Li: Phosphorylation profiling of systemin versus MAMP signaling reveals signaling specificity in plant..., Kartoniert / Broschiert
Phosphorylation profiling of systemin versus MAMP signaling reveals signaling specificity in plant immunity
(soweit verfügbar beim Lieferanten)
- Verlag:
- Cuvillier, 08/2025
- Einband:
- Kartoniert / Broschiert
- Sprache:
- Englisch
- ISBN-13:
- 9783689523114
- Artikelnummer:
- 12451360
- Umfang:
- 144 Seiten
- Gewicht:
- 197 g
- Maße:
- 210 x 148 mm
- Stärke:
- 8 mm
- Erscheinungstermin:
- 6.8.2025
- Hinweis
-
Achtung: Artikel ist nicht in deutscher Sprache!
Klappentext
Plasma membrane-localized pattern recognition receptors (PRRs) detect both microbe-associated molecular patterns (MAMPs) such as flg22 and chitin, and host-derived signals like systemin. While early signaling events (phosphorylation, ROS burst, MAPK activation) are largely similar, they lead to different biological outcomes: ¿ MAMPs activate innate immunity, ¿ Systemin induces wound and herbivore defense responses. To investigate how specificity arises, phospho-proteomics was applied in tomato cells (wild type vs. systemin receptor-deficient). In total, 4701 phospho-sites on 2119 proteins were identified. Using imputation and clustering, seven temporal phosphorylation patterns were observed: ¿ Systemin uniquely caused dephosphorylation at 1-15 min, ¿ flg22 triggered an early rapid phosphorylation response, ¿ Chitin mainly induced late phosphorylation events. Specificity was illustrated by three protein groups:
- RLCK/PBL kinases ¿ different family members respond in an elicitor-specific way.
- S-type anion channel SLAC1 ¿ carries a single regulatory site, differentially phosphorylated depending on the elicitor.
- Phosphatase PLL1a ¿ has multiple elicitor-specific phospho-sites (flg22: Ser50-59, chitin: Ser86-89, systemin: Ser163-181). Network analysis suggested that PLL1a regulates RBOHs, which was functionally validated using phospho-mimic / dead PLL1 mutants in Nicotiana.
Anmerkungen:
Bitte beachten Sie, dass auch wir der Preisbindung unterliegen und kurzfristige Preiserhöhungen oder -senkungen an Sie weitergeben müssen.