Precision Molecular Pathology of Aggressive B-Cell Lymphomas, Kartoniert / Broschiert

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Section I. Background.- Historical Perspectives in B-Cell Lymphoma Classification: From Hodgkin to WHO.- Revisions to the Classification of Aggressive B-Cell Lymphomas.- Section II. Methods.- Cytogenetics and FISH in Precision Molecular Pathology of Aggressive B-Cell Lymphomas.- Introduction to Next Generation Sequencing.- Next Generation Sequencing-Based Methods for the Detection of B-Cell Clonality.- Next Generation Sequencing Detection of Copy Number Variants and Translocations.- RNA-Seq and RNA Expression Profiling.- Flow Cytometry Applications in the Diagnosis and Classification of Aggressive B-Cell Lymphoma.- Section III. Molecular Characteristics of Specific Large B-Cell Lymphoma Subtypes.- High-Grade B-Cell Lymphomas.- Precision Medicine in Burkitt and Burkitt-Like Lymphomas.- Precision Medicine in Diffuse Large B-Cell Lymphoma.- B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma and Classic Hodgkin Lymphoma.- Special Sites: Primary Mediastinal Large B-Cell Lymphoma, Primary CNS Diffuse Large B-Cell Lymphoma, and Primary Testicular Diffuse Large B-Cell Lymphoma.- Molecular Pathology of Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type.- Epstein-Barr Virus-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified.- Lymphomatoid Granulomatosis.- T-Cell / Histiocyte-Rich Large B-Cell Lymphoma.- ALK Positive Large B-Cell Lymphoma.- HHV8-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified / KSHV/HHV8-Positive Diffuse Large B-Cell Lymphoma.- Large B-Cell Lymphomas With IRF4 Rearrangements.- Diffuse Large B-Cell Lymphoma Associated With Chronic Inflammation and Fibrin-Associated Large B-Cell Lymphoma.- Section IV. Immune Deficiency Related Lymphoproliferative Disease.- Plasmablastic Lymphoma.- Genetic Landscape of Post-Transplant Lymphoproliferative Disorders.- Epstein-Barr Virus-Positive Mucocutaneous Ulcer.- Section V. Emerging Molecular Technologies.- Circulating Tumor DNA in Lymphoma.