National Academies of Sciences Engineering and Medicine: Examining Glucagon-Like Peptide-1 Receptor (Glp-1r)..., Kartoniert / Broschiert
Examining Glucagon-Like Peptide-1 Receptor (Glp-1r) Agonists for Central Nervous System Disorders
- Proceedings of a Workshop
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- Auswahl:
- Sheena M Posey Norris, Eva Childers, Robert Pool
- Verlag:
- National Academies Press, 11/2025
- Einband:
- Kartoniert / Broschiert
- Sprache:
- Englisch
- ISBN-13:
- 9780309735056
- Umfang:
- 118 Seiten
- Erscheinungstermin:
- 27.11.2025
- Hinweis
-
Achtung: Artikel ist nicht in deutscher Sprache!
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Klappentext
Glucagon-like peptide-1 receptor (GLP-1R) agonists, originally developed for type 2 diabetes patients and popularized by their ability to rapidly reduce body weight in patients with obesity, have recently received a lot of national attention. Repurposing GLP-1R agonists to treat some central nervous disorders is promising, but comparatively understudied. At a September 2024 workshop, the National Academies Forum on Neuroscience and Nervous System Disorders reviewed the current knowledge and research gaps about the mechanisms of action of GLP-1R agonists in the brain, and the evidence of their clinical efficacy for eating disorders, neurodegenerative diseases, substance use disorders, and pain.
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