Mona El-Banna: Parkinson's Disease: Insights into Pathogenesis and Symptomatology, Kartoniert / Broschiert
Parkinson's Disease: Insights into Pathogenesis and Symptomatology
Buch
- Parkinson's Disease: Understanding Pathogenesis, Symptoms, and Challenges
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(soweit verfügbar beim Lieferanten)
(soweit verfügbar beim Lieferanten)
Aktueller Preis: EUR 47,36
- Verlag:
- Scholars' Press, 01/2025
- Einband:
- Kartoniert / Broschiert
- Sprache:
- Englisch
- ISBN-13:
- 9783639714111
- Artikelnummer:
- 12181432
- Umfang:
- 72 Seiten
- Gewicht:
- 125 g
- Maße:
- 220 x 150 mm
- Stärke:
- 5 mm
- Erscheinungstermin:
- 15.1.2025
- Hinweis
-
Achtung: Artikel ist nicht in deutscher Sprache!
Klappentext
Parkinson's disease (PD) is a common neurodegenerative disorder affecting over 10 million people worldwide, with prevalence rising with age. It is characterized by motor symptoms like bradykinesia and rigidity, and non-motor symptoms driven by dopaminergic neuron loss in the substantia nigra pars compacta (SNpc). Key pathological features include alpha-synuclein aggregation into Lewy bodies, mitochondrial dysfunction, oxidative stress, and neuroinflammation. As PD progresses, dopamine depletion worsens, leading to advanced motor complications and non-motor impairments. Current treatments alleviate symptoms but do not prevent neurodegeneration. Understanding the mechanisms of alpha-synuclein aggregation, mitochondrial dysfunction, and neuroinflammation is essential for developing effective disease-modifying therapies.Mehr von Mona El-Banna
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Mona El-Banna
Parkinson's Disease: Insights into Pathogenesis and Symptomatology
Aktueller Preis: EUR 47,36